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enduracidin B


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  • Norine ID: NOR00762
  • Family: enduracidin
  • Synonym(s): enduracidin B;
  • Activity: antibiotic
  • Class: lipopeptide
  • Formula: C108H140Cl2N26O31
  • Molecular weight: 2369.3289 g/mol
  • Comment: Ramoplanin is known to show a similar primary structure than enduracidins.
  • Source: norine
  • Entry information:
    • status: curated
    • last modification date: 2008-08-01
      Norine team [ProBioGEM (UPRES EA 1026 USTL), France, LIFL (UMR CNRS 8022 / Univ. Lille1), France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 18
  • Smiles: CCC(C)CCCCC=CC=CC(=O)NC(CC(=O)O)C(=O)NC3C(C)OC(=O)C(NC(=O)C(C)NC(=O)C(CC1CNC(N)=N1)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC2CNC(N)=N2)NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(CCCN)NC(=O)C(NC3(=O))c4ccc(O)cc4)C(C)O)c5ccc(O)cc5)c6ccc(O)cc6)C(C)O)c7ccc(O)cc7)c8cc(c(O)c(c8)Cl)Cl)c9ccc(O)cc9
  • Monomeric composition :
    1
    aC13:2(2.t4)
    2
    Asp
    3
    Thr
    4
    D-Hpg
    5
    D-Orn
    6
    D-aThr
    7
    Hpg
    8
    D-Hpg
    9
    aThr
    10
    Cit
    11
    D-End
    12
    Hpg
    13
    D-Ser
    14
    Cl2-Hpg
    15
    Gly
    16
    End
    17
    D-Ala
    18
    Hpg
  • Graph representation: aC13:2(2.t4),Asp,Thr,D-Hpg,D-Orn,D-aThr,Hpg,D-Hpg,aThr,Cit,D-End,Hpg,D-Ser,Cl2-Hpg,Gly,End,D-Ala,Hpg @1 @0,2 @1,3,17 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @2,16

  • Atomic structure:
    Chemical structure
  • Streptomyces fungicidicus
  • gram: positive
  • taxid: 68203 (view NCBI taxonomy browser)

  • Links between organisms producing the enduracidin B: Streptomyces fungicidicus
  • The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus
    Zabriskie TM, Yin X, Microbiology , 2006, Oct,152(Pt 10):2969-83.
    pubMed: 17005978


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