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cyclosporin L


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  • Norine ID: NOR00043
  • DOI: 10.26097/nor00043
  • Family: cyclosporin
  • Synonym(s): cyclosporin L;
  • Activity: unknown
  • Class: peptide
  • Formula: C61H109N11O12
  • Monoisotopic mass: 1187.825718007 g/mol
  • Comment: Natural analogs of cyclosporin A are obtain in different nutrient broths
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 11
  • Smiles: CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

  • Graph inference:



  • Monomeric composition :
    1
    D-Ala
    2
    NMe-Leu
    3
    NMe-Leu
    4
    NMe-Val
    5
    Bmt
    6
    Abu
    7
    NMe-Gly
    8
    NMe-Leu
    9
    Val
    10
    NMe-Leu
    11
    Ala
  • Graph representation: D-Ala,NMe-Leu,NMe-Leu,NMe-Val,Bmt,Abu,NMe-Gly,NMe-Leu,Val,NMe-Leu,Ala @1,10 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @0,9

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Tolypocladium inflatum
  • gram:
  • synonyms: Tolypocladium niveum,Beauveria nivea
  • taxid: 29910 (view NCBI taxonomy browser)

  • Links between organisms producing the cyclosporin L: Tolypocladium inflatum
  • Multifunctional Peptide Synthetases
    von Dohren H, Keller U, Vater J, Zocher R, Chemical reviews , 1997, Nov 10,97(7):2675-2706.
    pubMed: 11851477


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