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oscillamide C


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  • Norine ID: NOR00277
  • DOI: 10.26097/nor00277
  • Family: oscillamide
  • Synonym(s): oscillamide C;
  • Activity: protease inhibitor
  • Class: peptide
  • Formula: C49H68N10O10
  • Monoisotopic mass: 956.511988446 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2019-04-04 by Maude Pupin [Université Lille 1, France, CRIStAL (UMR CNRS 9189), ex-LIFL, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 7
  • Smiles: CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)NCCCC[C@H](C(=O)N1)NC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)CC2=CC=CC=C2)CCC3=CC=C(C=C3)O)C)CCC4=CC=C(C=C4)O

  • Graph inference:



  • Monomeric composition :
    1
    Phe
    2
    NMe-Hty
    3
    Hty
    4
    Ile
    5
    D-NFo-Lys
    6
    Arg
  • Graph representation: Phe,NMe-Hty,Hty,Ile,D-NFo-Lys,Arg @1,4 @0,2 @1,3 @2,4 @0,3,5 @4

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Oscillatoria agardhii
  • gram: negative
  • synonyms: Planktothrix agardhii
  • taxid: 1160 (view NCBI taxonomy browser)

  • Nodularia spumigena
  • gram: negative
  • synonyms: Nodularia sp. NSOR-12
  • taxid: 70799 (view NCBI taxonomy browser)

  • Links between organisms producing the oscillamide C: Oscillatoria agardhii, Nodularia spumigena
  • Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp.
    Kaya K, Sano T, Usui T, Ueda K, Osada H, Journal of natural products , 2001, Aug,64(8):1052-5.
    DOI: 10.1021/np0005356
    pubMed: 11520225


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