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White Line Inducing Principle


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  • Norine ID: NOR00337
  • DOI: 10.26097/nor00337
  • Family: viscosin
  • Synonym(s): White Line Inducing Principle;
  • Activity: surfactant, antimicrobial
  • Class: lipopeptide
  • Formula: C54H95N9O16
  • Monoisotopic mass: 1125.689678037 g/mol
  • Comment: WLIP is structurally similar to viscosin, except for the chirality of leucine in position 5 which has D configuration in WLIP and L configuration in viscosin.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 10
  • Monomeric composition :
    1
    C10:0-OH(3)
    2
    Leu
    3
    D-Glu
    4
    D-aThr
    5
    D-Val
    6
    D-Leu
    7
    D-Ser
    8
    Leu
    9
    D-Ser
    10
    Ile
  • Graph representation: C10:0-OH(3),Leu,D-Glu,D-aThr,D-Val,D-Leu,D-Ser,Leu,D-Ser,Ile @1 @0,2 @1,3 @2,4,9 @3,5 @4,6 @5,7 @6,8 @7,9 @3,8

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Pseudomonas reactans
  • gram: negative
  • taxid: 117680 (view NCBI taxonomy browser)

  • Links between organisms producing the White Line Inducing Principle: Pseudomonas reactans
  • WLIP and tolaasin I, lipodepsipeptides from Pseudomonas reactans and Pseudomonas tolaasii, permeabilise model membranes
    Coraiola M, Lo Cantore P, Lazzaroni S, Evidente A, Iacobellis NS, Dalla Serra M, Biochimica et biophysica acta , 2006, Jul 14, [Epub ahead of print]
    DOI: 10.1016/j.bbamem.2006.06.023
    pubMed: 16925979


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