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halipeptin A


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  • Norine ID: NOR00452
  • DOI: 10.26097/nor00452
  • Family: halipeptin
  • Synonym(s): halipeptin A;
  • Activity: antiinflammatory
  • Class: peptide
  • Formula: C31H54N4O7S
  • Monoisotopic mass: 626.3713208019999 g/mol
  • Comment: Halipeptin is a putative NRPS product (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 5
  • Smiles: CCC[C@@H](CC[C@@H](C)[C@H]1C(C(=O)N[C@H](C2=N[C@@](CS2)(C(=O)N([C@H](C(=O)N[C@H](C(=O)O1)C)[C@@H](C)CCO)C)C)C)(C)C)OC

  • Graph inference:



  • Monomeric composition :
    1
    C10:0-Me(2.2.4)-OH(3)-OMe(7)
    2
    Ala
    3
    aMe-Cys
    4
    NMe-OH-Ile
    5
    Ala
  • Graph representation: C10:0-Me(2.2.4)-OH(3)-OMe(7),Ala,aMe-Cys,NMe-OH-Ile,Ala @1,4 @0,2 @1,3 @2,4 @0,3

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Haliclona sp.
  • taxid: 34490 (view NCBI taxonomy browser)

  • Links between organisms producing the halipeptin A: Haliclona sp.
  • Structural revision of halipeptins: Synthesis of the thiazoline unit and isolation of halipeptin C
    Bifulco G, Gomez-Paloma L, Randazzo A, Della Monica C, Cimino P, Aquino M, Izzo I, De Riccardis F, Tetrahedron letters , 2002, 43 (33), pp. 5707-5710


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