Norine

home > NRP > norine

phakellistatin 2


Get HTML  Get XML  Get Json  Import model in MyNorine  Modify

  • Norine ID: NOR00524
  • Family: phakellistatin
  • Synonym(s): phakellistatin 2;
  • Activity: antitumor
  • Class: peptide
  • Formula: C45H62N7O8
  • Monoisotopic mass: 828.465986995 g/mol
  • Comment: Phakellistatins are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Smiles: CCC(C)C3NC(=O)C6CCCN6(C(=O)C(Cc1ccccc1)NC(=O)C5CCCN5(C(=O)C(Cc2ccc(O)cc2)NC(=O)C4CCCN4(C(=O)C(NC3(=O))C(C)CC)))

  • Graph inference:



  • Monomeric composition :
    1
    Pro
    2
    Phe
    3
    Pro
    4
    Ile
    5
    Ile
    6
    Pro
    7
    Tyr
  • Graph representation: Pro,Phe,Pro,Ile,Ile,Pro,Tyr @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
    Chemical structure
  • Stylotella aurantium

  • Phakellia sp.

  • Links between organisms producing the phakellistatin 2: Stylotella aurantium, Phakellia sp.
  • Two distinct conformers of the cyclic heptapeptide phakellistatin 2 isolated from the fijian marine sponge stylotellaaurantium
    Tabudravu JN, Morris LA, Kettenes-van den Bosch JJ, Jaspars M, Smith N, The Journal of organic chemistry , 2002, Nov 29,67(24):8593-601.
    pubMed: 12444643


back Return to annotations search