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tuberactinomycin O


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  • Norine ID: NOR00636
  • Family: tuberactinomycin
  • Synonym(s): tuberactinomycin O;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C25H43N13O9
  • Monoisotopic mass: 669.330670039 g/mol
  • Comment: The tuberactinomycin antibiotics are essential components in the drug arsenal against Mycobacterium tuberculosis infections and are specifically used for the treatment of multidrug-resistant tuberculosis.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 6
  • Smiles: NCCCC(N)CC(=O)NC1CNC(=O)C(NC(=O)C(=CNC(N)=O)NC(=O)C(CO)NC(=O)C(CO)NC1(=O))C2CCN=C(N)N2

  • Graph inference:



  • Monomeric composition :
    1
    bLys
    2
    Dpr
    3
    Ser
    4
    Ser
    5
    bU-dAla
    6
    Cap
  • Graph representation: bLys,Dpr,Ser,Ser,bU-dAla,Cap @1 @0,2,5 @1,3 @2,4 @3,5 @1,4

  • Atomic structure:
    Chemical structure
  • Streptomyces
  • gram: positive
  • synonyms: Chainia
  • taxid: 1883 (view NCBI taxonomy browser)

  • Links between organisms producing the tuberactinomycin O: Streptomyces
  • Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster
    Thomas MG, Chan YA, Ozanick SG, Antimicrobial agents and chemotherapy , 2003, Sep,47(9):2823-30.
    pubMed: 12936980


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