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chloroorienticin B


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  • Norine ID: NOR00688
  • Family: orienticin
  • Synonym(s): chloroorienticin B;
  • Activity: antibiotic
  • Class: glycopeptide
  • Formula: C66H75Cl2N9O24
  • Monoisotopic mass: 1447.430199793 g/mol
  • Comment: Two bonds of the central Hpg are due to oxidative ring closure.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: other
  • Number of monomers: 9
  • Smiles: CNC(CC(C)C)C(=O)NC2C(=O)NC(CC(N)=O)C(=O)NC7c4cc(Oc1ccc(cc1Cl)C2(O))c(OC3OC(CO)C(O)C(O)C3(O))c(c4)Oc5ccc(cc5Cl)C(OC6CC(C)(N)C(O)C(C)O6)C9NC(=O)C(NC7(=O))c8ccc(O)c(c8)c%10c(O)cc(O)cc%10(C(NC9(=O))C(=O)O)

  • Graph inference:



  • Monomeric composition :
    1
    Asn
    2
    bOH-Cl-Tyr
    3
    NMe-Leu
    4
    Hpg
    5
    D-Glc
    6
    bOH-Cl-Tyr
    7
    Ere
    8
    Dhpg
    9
    Hpg
  • Graph representation: Asn,bOH-Cl-Tyr,NMe-Leu,Hpg,D-Glc,bOH-Cl-Tyr,Ere,Dhpg,Hpg @1,3 @0,3,2 @1 @1,0,4,5,8 @3 @3,7,6,8 @5 @8,5 @3,7,5

  • Atomic structure:
    Chemical structure
  • Nocardia orientalis
  • gram: positive
  • synonyms: Amycolatopsis orientalis,Streptomyces orientalis,Amycolatopsis orientalis orientalis
  • taxid: 31958 (view NCBI taxonomy browser)

  • Links between organisms producing the chloroorienticin B: Nocardia orientalis
  • New glycopeptide antibiotics: II. The isolation and structures of chloroorienticins
    Kobayashi M, Tsuji N, Kamigauchi T, Terui Y, The Journal of antibiotics , 1988, Oct,41(10):1506-10.
    pubMed: 3272137


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