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Orfamide A


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  • Norine ID: NOR01255
  • Family: Orfamide
  • Synonym(s): Orfamide A;
  • Activity: antibiotic, surfactant
  • Class: lipopeptide
  • Formula: C64H114N10O17
  • Monoisotopic mass: 1294.8363422720001 g/mol
  • Comment:
  • Source: mynorine
  • Contributor (creation): Valerie Leclere [Charles Viollette Institute, ProBioGEM team, Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 11
  • Smiles: CCCCCCCCCCCC(CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H]1[C@@H](OC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)[C@H](C)CC)CC(C)C)CO)CC(C)C)CC(C)C)CO)C(C)C)C)O

  • Graph inference:



  • Monomeric composition :
    1
    Leu
    2
    Leu
    3
    Leu
    4
    D-Glu
    5
    D-aThr
    6
    D-aIle
    7
    C14:0-OH(3)
    8
    D-Ser
    9
    Leu
    10
    D-Ser
    11
    Val
  • Graph representation: Leu,Leu,Leu,D-Glu,D-aThr,D-aIle,C14:0-OH(3),D-Ser,Leu,D-Ser,Val @3,6 @7,8 @5,7 @0,4 @3,5,10 @2,4 @0 @1,2 @1,9 @8,10 @4,9

  • Atomic structure:
    Chemical structure
  • Pseudomonas fluorescens Pf-5
  • gram: negative
  • synonyms:
  • taxid: 220664 (view NCBI taxonomy browser)

  • Links between organisms producing the Orfamide A: Pseudomonas fluorescens Pf-5
  • The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters
    Loper JE, Gross H, Stockwell VO, Henkels MD, Nowak-Thompson, ChemBiol , 2007, 14; 53-63
    pubMed: 17254952


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