Iedera is a subset seed/vectorized subset seed design tool, that allows to design spaced seeds, transition spaced seeds, and vector seeds devoted to DNA and protein similarity search. This command line tool is implemented in C++ and provided for research purposes only. Help on this program can be obtained with the --help (-h) parameter, or from the homepage : http://bioinfo.lifl.fr/yass/iedera.php The reference paper for the framework of this tool is [G. Kucherov, L. Noe, M. Roytberg, A unifying framework for seed sensitivity and its application to subset seeds. Journal of Bioinformatics and Computational Biology, 2006]