Norine

home > NRP > norine

alamethicin F30


Get HTML  Get XML  Get Json  Import model in MyNorine  Modify

  • Norine ID: NOR00010
  • Family: alamethicin
  • Synonym(s): alamethicin F30;
  • Activity: antibiotic
  • Class: peptaibol
  • Formula: C92H150N22O26
  • Monoisotopic mass: 1979.1091630820001 g/mol
  • Comment: The natural alpha-helical peptide antibiotic alamethicin forms voltage-gated ion channels in lipid membranes.
  • Source: norine
  • Entry information:
  • Type: linear
  • Number of monomers: 20
  • Smiles: C[C@H](C(=O)N[C@H](CCC(=O)N)C(=O)NC(C)(C)C(=O)N[C@H](C(C)C)C(=O)NC(C)(C)C(=O)NCC(=O)N[C@H](CC(C)C)C(=O)NC(C)(C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](CCC(=O)N)C(=O)N[C@H](CC2=CC=CC=C2)CO)NC(=O)C(C)(C)NC(=O)[C@@H](C)NC(=O)C(C)(C)NC(=O)[C@H]3CCCN3C(=O)C(C)(C)NC(=O)C

  • Smiles2Monomer  Run Smiles2Monomers to infer graph

  • Monomeric composition and PDB SEQRES:
    gra
    1
    Ac-Aib
    1 2
    ACE AIB
    2
    Pro
    3
    PRO
    3
    Aib
    4
    AIB
    4
    Ala
    5
    ALA
    5
    Aib
    6
    AIB
    6
    Ala
    7
    ALA
    7
    Gln
    8
    GLN
    8
    Aib
    9
    AIB
    9
    Val
    10
    VAL
    10
    Aib
    11
    AIB
    11
    Gly
    12
    GLY
    12
    Leu
    13
    LEU
    13
    Aib
    14
    AIB
    14
    Pro
    15
    PRO
    15
    Val
    16
    VAL
    16
    Aib
    17
    AIB
    17
    Aib
    18
    AIB
    18
    Glu
    19
    GLU
    19
    Gln
    20
    GLN
    20
    Pheol
    21
    PHL
  • Graph representation: Ac-Aib,Pro,Aib,Ala,Aib,Ala,Gln,Aib,Val,Aib,Gly,Leu,Aib,Pro,Val,Aib,Aib,Glu,Gln,Pheol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13,15 @14,16 @15,17 @16,18 @17,19 @18

  • Atomic structure:
    Chemical structure
  • Trichoderma viride
  • synonyms: Trichoderma lignorum
  • taxid: 5547 (view NCBI taxonomy browser)

  • Links between organisms producing the alamethicin F30: Trichoderma viride
  • Analysis of the lipophilic peptaibol alamethicin by nonaqueous capillary electrophoresis-electrospray ionization-mass spectrometry
    Psurek A, Neususs C, Pelzing M, Scriba GK, Electrophoresis , 2005, Nov,26(22):4368-78.
    pubMed: 16287177


back Return to annotations search