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polytheonamide B


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  • Norine ID: NOR00669
  • Family: polytheonamide
  • Synonym(s): polytheonamide B;
  • Activity: antitumor
  • Class: peptide
  • Formula: C219H376N60O72S
  • Monoisotopic mass: 5030.732575816 g/mol
  • Comment: Polytheonamides are by far the largest nonribosomal peptides. Two variants (A and C) exist and are isomeric.
  • Source: norine
  • Entry information:
    • status: curated
    • last modification date: 2008-10-03
      Norine team [ProBioGEM (UPRES EA 1026 USTL), France, LIFL (UMR CNRS 8022 / Univ. Lille1), France]
    • view all entry history
  • Theonella swinhoei
  • taxid: 37505 (view NCBI taxonomy browser)

  • Links between organisms producing the polytheonamide B: Theonella swinhoei
  • Polytheonamides A and B, highly cytotoxic, linear polypeptides with unprecedented structural features, from the marine sponge, Theonella swinhoei
    Matsunaga S, Fusetani N, Hamada T, Yano G, Journal of the American Chemical Society , 2005, Jan 12,127(1):110-8.
    pubMed: 15631460


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