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Quinomycin A


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  • Norine ID: NOR01905
  • Family: unknown
  • Synonym(s):
  • Activity:
  • Class:
  • Monoisotopic mass: 1101.25706 g/mol
  • Source: StreptomeDB
  • Contributor (creation): Norine Bot [CRIStAL (UMR CNRS 9189), ex-LIFL, France]
  • Entry information:
  • Type:
  • Smiles: CSC1SCC2N(C)C(=O)C(C)NC(=O)C(COC(=O)C(N(C(=O)C1N(C)C(=O)C(C)NC(=O)C(COC(=O)C(N(C2=O)C)C(C)C)NC(=O)c1cnc2c(n1)cccc2)C)C(C)C)NC(=O)c1cnc2c(n1)cccc2

  • Graph inference:



  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Streptomyces echinatus
  • gram: positive
  • taxid: 67293 (view NCBI taxonomy browser)

  • Streptomyces
  • gram: positive
  • taxid: 68187 (view NCBI taxonomy browser)

  • Links between organisms producing the Quinomycin A: Streptomyces echinatus, Streptomyces
  • Studies on antibiotic biosynthesis by protoplasts and resting cells of Streptomyces echinatus. Part II. Effect of chromophore precursors.
    Canadian journal of microbiology , 1986, 32(5):363-72
    DOI: 10.1139/m86-071
    pubMed: 3719457
  • Functional cross-talk between fatty acid synthesis and nonribosomal peptide synthesis in quinoxaline antibiotic-producing streptomycetes.
    The Journal of biological chemistry , 2005, 280(6):4339-49
    DOI: 10.1074/jbc.M411026200
    pubMed: 15569690
  • Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus.
    Biotechnology progress , 2008, 24(6):1226-31
    DOI: 10.1002/btpr.34
    pubMed: 19194935
  • Echinomycin: the first bifunctional intercalating agent in clinical trials.
    Investigational new drugs , 1985, 3(4):403-10
    pubMed: 3910610
  • Directed biosynthesis of novel derivatives of echinomycin by Streptomyces echinatus. I. Effect of exogenous analogues of quinoxaline-2-carboxylic acid on the fermentation.
    Canadian journal of microbiology , 1984, 30(4):439-50
    DOI: 10.1139/m84-065
    pubMed: 6744120
  • Recognition elements that determine affinity and sequence-specific binding to DNA of 2QN, a biosynthetic bis-quinoline analogue of echinomycin.
    Anti-cancer drug design , 1999, 14(3):291-303
    pubMed: 10500504
  • Influence of isoleucine upon quinomycin biosynthesis by Streptomyces sp. 732.
    Journal of bacteriology , 1967, 93(4):1327-31
    pubMed: 6032510
  • Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product.
    Journal of the American Chemical Society , 2009, 131(26):9347-53
    DOI: 10.1021/ja902261a
    pubMed: 19514719
  • [Coculture of actinomycetes with Bacillus subtilis and its effect on the bioactive secondary metabolites].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology , 2009, 25(6):932-40
    pubMed: 19777825
StreptomeDB  5



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