Norine

• Type:
• Smiles: Cc1ccc2c(c1O)NC(O)C1N(C2=O)C=C(C1)/C=C/C(=O)N
  
  
• Graph inference:


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• Atomic structure:

vizualisation:

• Streptomyces
• gram: positive
• taxid: 68187 (view NCBI taxonomy browser)

• Streptomyces refuineus
• gram: positive
• taxid: 223297 (view NCBI taxonomy browser)

• Links between organisms producing the Antramycin: Streptomyces, Streptomyces refuineus

• Sensitivity and permeability of the anthramycin producing organism Streptomyces refuineus to anthramycin and structurally related antibiotics.
  The Journal of antibiotics , 1981, 34(9):1171-4
  DOI: 10.7164/antibiotics.34.1171
  pubMed: 6895748

• Benzodiazepine biosynthesis in Streptomyces refuineus.
  Chemistry & biology , 2007, 14(6):691-701
  DOI: 10.1016/j.chembiol.2007.05.009
  pubMed: 17584616

• Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis.
  Natural product reports , 2009, 26(5):628-60
  DOI: 10.1039/b822528a
  pubMed: 19387499

• Development of a gene cloning system in a fast-growing and moderately thermophilic Streptomyces species and heterologous expression of Streptomyces antibiotic biosynthetic gene clusters.
  BMC microbiology , 2011, 11:243
  DOI: 10.1186/1471-2180-11-243
  pubMed: 22032628

• Regulation of tyrosine biosynthesis by phenylalanine in anthramycin-producing Streptomyces refuineus.
  The Journal of antibiotics , 1980, 33(6):579-84
  DOI: 10.7164/antibiotics.33.579
  pubMed: 7419472

• Cholecystokinin antagonism by anthramycin, a benzodiazepine antibiotic, in the central nervous system in mice.
  Brain research , 1989, 485(1):62-6
  DOI: 10.1016/0006-8993(89)90666-5
  pubMed: 2720404

• A heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin.
  Biochemistry , 2011, 50(41):8926-36
  DOI: 10.1021/bi201148a
  pubMed: 21919439

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