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actinomycin V


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  • Norine ID: NOR00232
  • Family: actinomycin
  • Synonym(s): actinomycin V;
  • Activity: antibiotic
  • Class: chromopeptide
  • Formula: C62H84N12O17
  • Monoisotopic mass: 1268.607739322 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: double cyclic
  • Number of monomers: 11
  • Smiles: CC(C)C6NC(=O)C(NC(=O)c3ccc(C)c4OC5=C(C)C(=O)C(N)=C(C(=O)NC1C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CC(=O)CN2(C(=O)C(NC1(=O))C(C)C))C5(=Nc34))C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C7CCCN7(C6(=O))

  • Graph inference:



  • Monomeric composition and PDB SEQRES:
    1
    Thr
    1
    THR
    2
    D-Val
    2
    DVA
    3
    4oxo-Pro
    3
    DPL
    4
    NMe-Gly
    4
    SAR
    5
    NMe-Val
    5
    MVA
    6
    ChrAct
    6
    PXZ
    7
    Thr
    7
    THR
    8
    D-Val
    8
    DVA
    9
    Pro
    9
    PRO
    10
    NMe-Gly
    10
    SAR
    11
    NMe-Val
    11
    MVA
  • Graph representation: Thr,D-Val,4oxo-Pro,NMe-Gly,NMe-Val,ChrAct,Thr,D-Val,Pro,NMe-Gly,NMe-Val @1,4,5 @0,2 @1,3 @2,4 @3,0 @0,6 @5,7,10 @6,8 @7,9 @8,10 @6,9

  • Atomic structure:
    Chemical structure
  • Streptomyces antibioticus
  • gram: positive
  • synonyms: Actinomyces antibioticus
  • taxid: 1890 (view NCBI taxonomy browser)

  • Streptomyces sp.
  • gram: positive
  • taxid: 1931 (view NCBI taxonomy browser)

  • Links between organisms producing the actinomycin V: Streptomyces antibioticus, Streptomyces sp.
  • Isolation and identification of oxoproline in actinomycin X2. (V). Hydrolysates
    Diegelmann R, Mauger A, Katz E, The Journal of antibiotics , 1969, Feb,22(2):85-7.
    pubMed: 4181575


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