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amphisin


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  • Norine ID: NOR00339
  • DOI: 10.26097/nor00339
  • Family: amphisin
  • Synonym(s): amphisin;
  • Activity: surfactant, antimicrobial
  • Class: lipopeptide
  • Formula: C66H114N12O20
  • Monoisotopic mass: 1394.827234148 g/mol
  • Comment: Amphisin is a close analogue of the cyclic lipopeptides tensin and pholipeptin produced by Pseudomonas fluorescens.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 12
  • Smiles: CCCCCCC[C@H](CC(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC(=O)O)C(=O)N[C@@H]1[C@H](OC(=O)[C@@H](NC(=O)[C@H](NC(=O)C(NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CC(C)C)CC(C)C)CO)CC(C)C)CCC(=O)N)CC(C)C)[C@H](C)CC)CC(=O)O)C)O

  • Graph inference:



  • Monomeric composition :
    1
    C10:0-OH(3)
    2
    D-Leu
    3
    D-Asp
    4
    D-aThr
    5
    D-Leu
    6
    D-Leu
    7
    D-Ser
    8
    Leu
    9
    D-Gln
    10
    Leu
    11
    Ile
    12
    Asp
  • Graph representation: C10:0-OH(3),D-Leu,D-Asp,D-aThr,D-Leu,D-Leu,D-Ser,Leu,D-Gln,Leu,Ile,Asp @1 @0,2 @1,3 @2,4,11 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @3,10

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Pseudomonas sp. DSS73
  • gram: negative
  • taxid: 173677 (view NCBI taxonomy browser)

  • Links between organisms producing the amphisin: Pseudomonas sp. DSS73
  • Cyclic lipoundecapeptide amphisin from Pseudomonas sp. strain DSS73
    Nielsen TH, Christophersen C, Sorensen J, Sorensen D, Gajhede M, Acta crystallographica. Section C, Crystal structure communications , 2001, Sep,57(Pt 9):1123-4. Epub 2001 Sep 11
    DOI: 10.1107/s0108270101010782
    pubMed: 11588392
  • Genes involved in cyclic lipopeptide production are important for seed and straw colonization by Pseudomonas sp. strain DSS73
    Nielsen TH, Nybroe O, Koch B, Hansen M, Sorensen J, Applied and environmental microbiology , 2005, Jul,71(7):4112-6.
    DOI: 10.1128/AEM.71.7.4112-4116.2005
    pubMed: 16000829


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