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foroxymithine


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  • Norine ID: NOR00622
  • DOI: 10.26097/nor00622
  • Family: foroxymithine
  • Synonym(s): foroxymithine;
  • Activity: siderophore
  • Class: peptide
  • Formula: C22H37N7O11
  • Monoisotopic mass: 575.255105061 g/mol
  • Comment: Foroxymithine is a putative NRPS product (no synthetase genes identified) and inhibits angiotensin I converting enzyme.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 4
  • Smiles: CC(=O)NC(CCCN(O)C=O)C(=O)NC(CO)C(=O)N(O)CCCC1NC(=O)C(CCCN(O)C=O)NC1(=O)

  • Graph inference:



  • Monomeric composition :
    1
    NAc-Fo-OH-Orn
    2
    Ser
    3
    OH-Orn
    4
    Fo-OH-Orn
  • Graph representation: NAc-Fo-OH-Orn,Ser,OH-Orn,Fo-OH-Orn @1 @0,2 @1,3,3 @2,2

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Streptomyces nitrosporeus
  • gram: positive
  • taxid: 28894 (view NCBI taxonomy browser)

  • Links between organisms producing the foroxymithine: Streptomyces nitrosporeus
  • Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes
    Ogawa K, Iinuma H, Naganawa H, Hamada M, Takeuchi T, Umezawa H, Aoyagi T, Obata T, The Journal of antibiotics , 1985, Dec,38(12):1813-5.
    DOI: 10.7164/antibiotics.38.1813
    pubMed: 3005216


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