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globomycin


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  • Norine ID: NOR00646
  • DOI: 10.26097/nor00646
  • Family: globomycin
  • Synonym(s): globomycin;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C32H57N5O9
  • Monoisotopic mass: 655.415628447 g/mol
  • Comment: Globomycin is a putative NRPS product (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 6
  • Smiles: CCCCCCC1OC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)C1(C))C(C)CC)C(C)O

  • Graph inference:



  • Monomeric composition :
    1
    Gly
    2
    aThr
    3
    Ser
    4
    aIle
    5
    NMe-Leu
    6
    C9:0-Me(2)-OH(3)
  • Graph representation: Gly,aThr,Ser,aIle,NMe-Leu,C9:0-Me(2)-OH(3) @1,5 @0,2 @1,3 @2,4 @3,5 @0,4

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Streptomyces cinnamoneus
  • gram: positive
  • synonyms: Streptoverticillium cinnamoneum,Verticillomyces cinnamomeus forma cinnamomeus,
  • taxid: 53446 (view NCBI taxonomy browser)

  • Streptomyces halstedii
  • gram: positive
  • taxid: 1944 (view NCBI taxonomy browser)

  • Streptomyces sp.
  • gram: positive
  • synonyms:
  • taxid: 1931 (view NCBI taxonomy browser)

  • Links between organisms producing the globomycin: Streptomyces cinnamoneus, Streptomyces halstedii, Streptomyces sp.
  • Crystal structure and total synthesis of globomycin: Establishment of relative and absolute configurations
    Kogen H, Kiho T, Nakayama M, Furukawa Y, Kinoshita T, Inukai M, Journal of the American Chemical Society , 2000, 122 (41), pp. 10214-10215


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