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A54145 B1


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  • Norine ID: NOR00716
  • DOI: 10.26097/nor00716
  • Family: A54145
  • Synonym(s): A54145 B1;
  • Activity: antibiotic
  • Class: lipopeptide
  • Formula: C73H111N17O27
  • Monoisotopic mass: 1657.7835314309998 g/mol
  • Comment: A54145 products are antibiotics for the traitment of infections caused by gram-positive pathogens.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 14
  • Monomeric composition :
    1
    iC10:0
    2
    Trp
    3
    D-Glu
    4
    OH-Asn
    5
    Thr
    6
    NMe-Gly
    7
    Ala
    8
    Asp
    9
    D-Lys
    10
    OMe-Asp
    11
    Gly
    12
    D-Asn
    13
    3Me-Glu
    14
    Ile
  • Graph representation: iC10:0,Trp,D-Glu,OH-Asn,Thr,NMe-Gly,Ala,Asp,D-Lys,OMe-Asp,Gly,D-Asn,3Me-Glu,Ile @1 @0,2 @1,3 @2,4 @3,5,13 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @4,12

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Streptomyces fradiae
  • gram: positive
  • synonyms: Streptomyces roseoflavus,Streptomyces fradii,Actinomyces fradii,Streptomyces roseiflavus
  • taxid: 1906 (view NCBI taxonomy browser)

  • Links between organisms producing the A54145 B1: Streptomyces fradiae
  • Natural products to drugs: daptomycin and related lipopeptide antibiotics
    Baltz RH, Miao V, Wrigley SK, Natural product reports , 2005, Dec,22(6):717-41. Epub 2005 Nov 4.
    DOI: 10.1039/b416648p
    pubMed: 16311632


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