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  • Norine ID: NOR00025
  • DOI: 10.26097/nor00025
  • Family: Calcium dependent antibiotic
  • Synonym(s): CDA2b;
  • Activity: antibiotic
  • Class: lipopeptide
  • Formula: C67H82N14O29P
  • Monoisotopic mass: 1577.5109742319999 g/mol
  • Comment: CDA shares a similar structure and possibly a related mode of action to other acidic lipopeptide antibiotics, including daptomycin, friulimicins, and amphomycins.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Streptomyces roseosporus
  • gram: positive
  • synonyms: Streptomyces filamentosus,Streptomyces venezuelae subsp. roseospori,Streptomyces roseisporus
  • taxid: 67294 (view NCBI taxonomy browser)

  • Metarhizium anisopliae
  • gram:
  • synonyms:
  • taxid: 5530 (view NCBI taxonomy browser)

  • Streptomyces coelicolor
  • gram: positive
  • synonyms: Actinomyces coelicolor,Nocardia coelicolor,Cladothrix coelicolor,Streptothrix coelicolor
  • taxid: 1902 (view NCBI taxonomy browser)

  • Links between organisms producing the CDA2b: Streptomyces roseosporus, Metarhizium anisopliae, Streptomyces coelicolor
  • Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor
    Hojati Z, Milne C, Harvey B, Gordon L, Borg M, Flett F, Wilkinson B, Sidebottom PJ, Rudd BA, Hayes MA, Smith CP, Micklefield J, Chemistry and biology , 2002, Nov,9(11):1175-87.
    pubMed: 12445768

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