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cyclosporin O


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  • Norine ID: NOR00046
  • DOI: 10.26097/nor00046
  • Family: cyclosporin
  • Synonym(s): cyclosporin O;
  • Activity: immunomodulating
  • Class: peptide
  • Formula: C60H109N11O11
  • Monoisotopic mass: 1159.830803385 g/mol
  • Comment: Natural analogs of cyclosporin A are obtain in different nutrient broths
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 11
  • Monomeric composition :
    1
    D-Ala
    2
    NMe-Leu
    3
    NMe-Leu
    4
    NMe-Val
    5
    NMe-Leu
    6
    Nva
    7
    NMe-Gly
    8
    NMe-Leu
    9
    Val
    10
    NMe-Leu
    11
    Ala
  • Graph representation: D-Ala,NMe-Leu,NMe-Leu,NMe-Val,NMe-Leu,Nva,NMe-Gly,NMe-Leu,Val,NMe-Leu,Ala @1,10 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @0,9

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Tolypocladium inflatum
  • gram:
  • synonyms: Tolypocladium niveum,Beauveria nivea
  • taxid: 29910 (view NCBI taxonomy browser)

  • Links between organisms producing the cyclosporin O: Tolypocladium inflatum
  • Multifunctional Peptide Synthetases
    von Dohren H, Keller U, Vater J, Zocher R, Chemical reviews , 1997, Nov 10,97(7):2675-2706.
    pubMed: 11851477


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