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aureobasidin A


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  • Norine ID: NOR00281
  • DOI: 10.26097/nor00281
  • Family: aureobasidin
  • Synonym(s): aureobasidin A;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C60H92N8O11
  • Monoisotopic mass: 1100.688555826 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 9
  • Smiles: CCC(C)C3NC(=O)C4CCCN4(C(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc2ccccc2)NC(=O)C(C(C)C)N(C)C(=O)C(OC(=O)C(N(C)C(=O)C(CC(C)C)NC(=O)C(C(C)C)N(C)C3(=O))C(C)(C)O)C(C)CC)

  • Graph inference:



  • Monomeric composition :
    1
    D-Hmp
    2
    NMe-Val
    3
    Phe
    4
    NMe-Phe
    5
    Pro
    6
    aIle
    7
    NMe-Val
    8
    Leu
    9
    bOH-NMe-Val
  • Graph representation: D-Hmp,NMe-Val,Phe,NMe-Phe,Pro,aIle,NMe-Val,Leu,bOH-NMe-Val @1,8 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @0,7

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Aureobasidium pullulans
  • gram:
  • synonyms:
  • taxid: 5580 (view NCBI taxonomy browser)

  • Links between organisms producing the aureobasidin A: Aureobasidium pullulans
  • Aureobasidins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC-transporter
    Tiberghien F, Kurome T, Takesako K, Didier A, Wenandy T, Loor F, Journal of medicinal chemistry , 2000, Jun 29,43(13):2547-56.
    DOI: 10.1021/jm990955w
    pubMed: 10891114


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