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HC-toxin


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  • Norine ID: NOR00304
  • DOI: 10.26097/nor00304
  • Family: HC-toxin
  • Synonym(s): HC-toxin;
  • Activity: toxin
  • Class: peptide
  • Formula: C21H32N4O6
  • Monoisotopic mass: 436.232184776 g/mol
  • Comment: HC-toxin is required for pathogenicity of the filamentous fungus Cochliobolus carbonum on maize.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 4
  • Smiles: CC2NC(=O)C(C)NC(=O)C3CCCN3(C(=O)C(CCCCCC(=O)C1CO1)NC2(=O))

  • Graph inference:



  • Monomeric composition :
    1
    D-Pro
    2
    Ala
    3
    D-Ala
    4
    C10:0-NH2(2)-Ep(9)-oxo(8)
  • Graph representation: D-Pro,Ala,D-Ala,C10:0-NH2(2)-Ep(9)-oxo(8) @1,3 @0,2 @1,3 @0,2

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Cochliobolus carbonum
  • taxid: 5017 (view NCBI taxonomy browser)

  • Links between organisms producing the HC-toxin: Cochliobolus carbonum
  • The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kilobase open reading frame
    Walton JD, Scott-Craig JS, Panaccione DG, Pocard JA, The Journal of biological chemistry , 1992, Dec 25,267(36):26044-9.
    pubMed: 1281482


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