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syringomycin E


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  • Norine ID: NOR00356
  • Family: syringomycin
  • Synonym(s): syringomycin E;
  • Activity: surfactant, antibiotic
  • Class: lipopeptide
  • Formula: C53H85ClN14O17
  • Monoisotopic mass: 1224.590565074 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2008-08-19 by Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 10
  • Smiles: CCCCCCCCC(CC(=O)N[C@H]1COC(=O)[C@@H](NC(=O)[C@H](NC(=O)/C(=C/CC)/NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CO)CCN)CCN)CCCN=C(N)N)CC2=CC=CC=C2)C(C(=O)O)O)[C@@H](CCl)O)O

  • Graph inference:



  • Monomeric composition :
    1
    C12:0-OH(3)
    2
    Ser
    3
    D-Ser
    4
    Dab
    5
    D-Dab
    6
    Arg
    7
    Phe
    8
    dhAbu
    9
    OH-Asp
    10
    4Cl-Thr
  • Graph representation: C12:0-OH(3),Ser,D-Ser,Dab,D-Dab,Arg,Phe,dhAbu,OH-Asp,4Cl-Thr @1 @0,2,9 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @1,8

  • Atomic structure:
    Chemical structure
  • Pseudomonas syringae pv. syringae
  • gram: negative
  • taxid: 321 (view NCBI taxonomy browser)

  • Links between organisms producing the syringomycin E: Pseudomonas syringae pv. syringae
  • The structure of syringomycins A1, E and G
    Iacobellis NS, Ballio A, Bossa F, Pucci P, Segre AL, Grgurina I, Bachmann RC, Marino G, Simmaco M, Takemoto JY, FEBS letters , 1989, Sep 11,255(1):27-31.
    pubMed: 2676599
  • Characterization of the syringomycin synthetase gene cluster. A link between prokaryotic and eukaryotic peptide synthetases
    Grgurina I, Guenzi E, Galli G, Gross DC, Grandi G, The Journal of biological chemistry , 1998, Dec 4,273(49):32857-63.
    pubMed: 9830033


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