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dolastatin 12


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  • Norine ID: NOR00372
  • Family: dolastatin
  • Synonym(s): dolastatin 12;
  • Activity: antitumor
  • Class: peptide
  • Formula: C50H80N8O11
  • Monoisotopic mass: 968.594655442 g/mol
  • Comment: Dolastatin 11 and dolastatin 12 inhibit growth of the murine P388 lymphocytic leukemia.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2006-10-20 by Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Dolabella auricularia
  • taxid: 6511 (view NCBI taxonomy browser)

  • Links between organisms producing the dolastatin 12: Dolabella auricularia
  • Dolastatins. 26. Synthesis and stereochemistry of dolastatin 11
    Bates RB, Brusoe KG, Burns JJ, Caldera S, Cui W, Gangwar S, Gramme MR, Bontems R, Journal of the American Chemical Society , 1997, 119 (9), pp. 2111-2113


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