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apramide G


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  • Norine ID: NOR00411
  • DOI: 10.26097/nor00411
  • Family: apramide
  • Synonym(s): apramide G;
  • Activity: antitumor, toxin
  • Class: lipopeptide
  • Formula: C44H74N7O6S
  • Monoisotopic mass: 828.5421288350001 g/mol
  • Comment: Apramides are putative NRPS products (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: linear
  • Number of monomers: 8
  • Smiles: C[C@H](CCCCC#C)C(=O)N(C)[C@@H](C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1CCC[C@H]1C2=NC=CS2

  • Graph inference:



  • Monomeric composition :
    1
    C8:0:1(7)-Me(2)
    2
    NMe-Ala
    3
    NMe-Val
    4
    NMe-Val
    5
    NMe-Val
    6
    NMe-Val
    7
    NMe-Val
    8
    Pro-Thz
  • Graph representation: C8:0:1(7)-Me(2),NMe-Ala,NMe-Val,NMe-Val,NMe-Val,NMe-Val,NMe-Val,Pro-Thz @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Lyngbya majuscula
  • gram: negative
  • taxid: 158786 (view NCBI taxonomy browser)

  • Links between organisms producing the apramide G: Lyngbya majuscula
  • Apramides A-G, novel lipopeptides from the marine cyanobacterium Lyngbya majuscula
    Luesch H, Moore RE, Paul VJ, Yoshida WY, Journal of natural products , 2000, Aug,63(8):1106-12.
    DOI: 10.1021/np000078t
    pubMed: 10978206


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