Norine

home > NRP > norine

cyclotheonamide E3


Get HTML  Get XML  Get Json  Import model in MyNorine  Modify

  • Norine ID: NOR00477
  • Family: cyclotheonamide
  • Synonym(s): cyclotheonamide E3;
  • Activity: antithrombotic
  • Class: peptide
  • Formula: C40H60N10O9
  • Monoisotopic mass: 824.454473568 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 7
  • Smiles: CC[C@H](C)[C@@H]1C(=O)N[C@H](/C=C/C(=O)NC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)C(=O)N1)CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)CC(C)C)CC3=CC=C(C=C3)O

  • Graph inference:



  • Monomeric composition :
    1
    Pro
    2
    k-Arg
    3
    D-aIle
    4
    v-Tyr
    5
    Dpr
    6
    Ala
    7
    Isovaleric_acid
  • Graph representation: Pro,k-Arg,D-aIle,v-Tyr,Dpr,Ala,Isovaleric_acid @1,4 @0,2 @1,3 @2,4 @0,3,5 @4,6 @5

  • Atomic structure:
    Chemical structure
  • Theonella swinhoei
  • taxid: 37505 (view NCBI taxonomy browser)

  • Links between organisms producing the cyclotheonamide E3: Theonella swinhoei
  • Cyclotheonamides E2 and E3, new potent serine protease inhibitors from the marine sponge of the genus Theonella
    Nakao Y, Oku N, Matsunaga S, Fusetani N, Journal of natural products , 1998, May,61(5):667-70.
    DOI: 10.1021/np970544n
    pubMed: 9599274


back Return to annotations search