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hymenamide B


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  • Norine ID: NOR00538
  • DOI: 10.26097/nor00538
  • Family: hymenamide
  • Synonym(s): hymenamide B;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C42H54N8O10
  • Monoisotopic mass: 830.396289988 g/mol
  • Comment: Hymenamides are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Smiles: CC(C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N3CCC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC4=CC=CC=C4)CC(=O)N)CC5=CC=CC=C5)CCC(=O)O

  • Graph inference:



  • Monomeric composition :
    1
    Pro
    2
    Asn
    3
    Phe
    4
    Val
    5
    Glu
    6
    Phe
    7
    Pro
  • Graph representation: Pro,Asn,Phe,Val,Glu,Phe,Pro @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
    Chemical structure
  • Hymeniacidon sp.

  • Links between organisms producing the hymenamide B: Hymeniacidon sp.
  • Hymenamides A and B, new proline-rich cyclic heptapeptides from the Okinawan marine sponge Hymeniacidon sp.
    Kobayashi JI, Tsuda M, Nakamura T, Mikami Y, Shigemori H, Tetrahedron , 1993, 9 (12), pp. 2391-2402


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