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stylostatin 1


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  • Norine ID: NOR00549
  • DOI: 10.26097/nor00549
  • Family: stylostatin
  • Synonym(s): stylostatin 1;
  • Activity: antitumor
  • Class: peptide
  • Formula: C36H54N8O9
  • Monoisotopic mass: 742.4013753659999 g/mol
  • Comment: Stylostatin is a putative NRPS product (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Smiles: CCC(C)C2NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(Cc1ccccc1)NC(=O)C3CCCN3(C2(=O))

  • Graph inference:



  • Monomeric composition :
    1
    Pro
    2
    Phe
    3
    Asn
    4
    Ser
    5
    Leu
    6
    Ala
    7
    Ile
  • Graph representation: Pro,Phe,Asn,Ser,Leu,Ala,Ile @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
    Chemical structure
  • Stylotella aurantium

  • Links between organisms producing the stylostatin 1: Stylotella aurantium
  • Isolation and structure of stylostatin 1 from the Papua New Guinea marine sponge Stylotella aurantium
    Pettit GR, Doubek DL, Tackett LP, Schmidt JM, Herald DL, Srirangam JK, Erickson KL, Bakus GJ, Journal of Organic Chemistry , 1992, 57 (26), pp. 7217-7220


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