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geodiamolide TA


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  • Norine ID: NOR00616
  • DOI: 10.26097/nor00616
  • Family: geodiamolide
  • Synonym(s): geodiamolide TA;
  • Activity: antitumor, toxin
  • Class: peptide
  • Formula: C30H44ClN3O6
  • Monoisotopic mass: 577.291863865 g/mol
  • Comment: Geodiamolides are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: cyclic
  • Number of monomers: 4
  • Smiles: C[C@@H]\1C[C@@H](OC(=O)[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@H](C/C(=C1)/C)C)C)C)CC2=CC(=C(C=C2)O)Cl)C(C)C)C

  • Graph inference:



  • Monomeric composition :
    1
    C9:1(4)-Me(2.4.6)-OH(8)
    2
    Ala
    3
    D-Cl-NMe-Tyr
    4
    Val
  • Graph representation: C9:1(4)-Me(2.4.6)-OH(8),Ala,D-Cl-NMe-Tyr,Val @1,3 @0,2 @1,3 @0,2

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • hemiasterella minor

  • Links between organisms producing the geodiamolide TA: hemiasterella minor
  • Hemiasterlin and geodiamolide TA: two new cytotoxic peptides from the marine sponge hemiasterella minor
    Pannell LK, Benayahu Y, Kashman Y, Schleyer M, Talpir R, Tetrahedron letters , 1994, 35 (25), pp. 4453-4456


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