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tuberactinamine


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  • Norine ID: NOR00637
  • Family: tuberactinomycin
  • Synonym(s): tuberactinamine;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C19H31N11O8
  • Monoisotopic mass: 541.2357070229999 g/mol
  • Comment: The tuberactinomycin antibiotics are essential components in the drug arsenal against Mycobacterium tuberculosis infections and are specifically used for the treatment of multidrug-resistant tuberculosis.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 5
  • Smiles: NC(=O)NC=C1NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(N)CNC(=O)C(NC1(=O))C2CCN=C(N)N2

  • Graph inference:



  • Monomeric composition :
    1
    Dpr
    2
    Ser
    3
    Ser
    4
    bU-dAla
    5
    Cap
  • Graph representation: Dpr,Ser,Ser,bU-dAla,Cap @1,4 @0,2 @1,3 @2,4 @0,3

  • Atomic structure:
    Chemical structure
  • Streptomyces
  • gram: positive
  • synonyms: Chainia
  • taxid: 1883 (view NCBI taxonomy browser)

  • Links between organisms producing the tuberactinamine: Streptomyces
  • Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster
    Thomas MG, Chan YA, Ozanick SG, Antimicrobial agents and chemotherapy , 2003, Sep,47(9):2823-30.
    pubMed: 12936980


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