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pristinamycin IC


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  • Norine ID: NOR00678
  • DOI: 10.26097/nor00678
  • Family: pristinamycin I
  • Synonym(s): pristinamycin IC;
  • Activity: antibiotic
  • Class: peptide
  • Formula: C44H52N8O10
  • Monoisotopic mass: 852.380639924 g/mol
  • Comment: Pristinamycins I are members of the streptogramin B group.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 7
  • Smiles: CC3NC(=O)C(NC(=O)c1ncccc1(O))C(C)OC(=O)C(NC(=O)C5CC(=O)CCN5(C(=O)C(Cc2ccc(cc2)N(C)C)N(C)C(=O)C4CCCN4(C3(=O))))c6ccccc6

  • Graph inference:



  • Monomeric composition :
    1
    Hpa
    2
    Thr
    3
    D-Ala
    4
    Pro
    5
    NMe-Me2A-Phe
    6
    4oxo-Hpr
    7
    Ph-Gly
  • Graph representation: Hpa,Thr,D-Ala,Pro,NMe-Me2A-Phe,4oxo-Hpr,Ph-Gly @1 @0,2,6 @1,3 @2,4 @3,5 @4,6 @1,5

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Streptomyces
  • gram: positive
  • synonyms: Chainia
  • taxid: 1883 (view NCBI taxonomy browser)

  • Links between organisms producing the pristinamycin IC: Streptomyces
  • Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene
    de Crecy-Lagard V, Saurin W, Thibaut D, Gil P, Naudin L, Crouzet J, Blanc V, Antimicrobial agents and chemotherapy , 1997, Sep,41(9):1904-9.
    pubMed: 9303382


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