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eremomycin


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  • Norine ID: NOR00693
  • Family: eremomycin
  • Synonym(s): eremomycin;
  • Activity: antibiotic
  • Class: glycopeptide
  • Formula: C73H89ClN10O26
  • Monoisotopic mass: 1556.5638007799998 g/mol
  • Comment: Two bonds of the central Hpg are due to oxidative ring closure.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: other
  • Number of monomers: 10
  • Smiles: CNC(CC(C)C)C(=O)NC%11C(=O)NC(CC(N)=O)C(=O)NC3c9cc(Oc1ccc(cc1)C(OC2CC(C)(N)C(O)C(C)O2)C5NC(=O)C(NC3(=O))c4ccc(O)c(c4)c6c(O)cc(O)cc6(C(NC5(=O))C(=O)O))c(OC8OC(CO)C(O)C(O)C8(OC7CC(C)(N)C(O)C(C)O7))c(c9)Oc%10ccc(cc%10Cl)C%11(O)

  • Graph inference:



  • Monomeric composition :
    1
    Asn
    2
    bOH-Cl-Tyr
    3
    NMe-Leu
    4
    Hpg
    5
    D-Glc
    6
    Ere
    7
    bOH-Tyr
    8
    Ere
    9
    Dhpg
    10
    Hpg
  • Graph representation: Asn,bOH-Cl-Tyr,NMe-Leu,Hpg,D-Glc,Ere,bOH-Tyr,Ere,Dhpg,Hpg @1,3 @0,2,3 @1 @1,0,4,6,9 @3,5 @4 @3,8,7,9 @6 @6,9 @8,3,6

  • Atomic structure:
    Chemical structure
  • actinomycetes sp. INA 238
  • gram: positive

  • Links between organisms producing the eremomycin: actinomycetes sp. INA 238
  • Eremomycin:new glycopeptide antibiotic: chemical properties and structure
    Gause GF, Brazhnikova MG, Lomakina NN, Berdnikova TF, Fedorova GB, Tokareva NL, Borisova VN, Batta GY, The Journal of antibiotics , 1989, Dec,42(12):1790-7.
    pubMed: 2621162


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