Norine

home > NRP > norine

aciculitin B


Get HTML  Get XML  Get Json  Import model in MyNorine  Modify

  • Norine ID: NOR00718
  • Family: aciculitin
  • Synonym(s): aciculitin B;
  • Activity: antibiotic, toxin
  • Class: glycopeptide
  • Formula: C62H88N14O21
  • Monoisotopic mass: 1364.624845948 g/mol
  • Comment: Aciculitins are putative NRPS products (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2008-07-25 by Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: double cyclic
  • Number of monomers: 11
  • Smiles: CCCCCCC/C=C/C=C/[C@H]([C@@H](C(=O)N/C(=C/C)/C(=O)N[C@H]1[C@@H](NC(=O)[C@@H]2CC3=C(C4=C(C=CC(=C4)CC(C(=O)N/C(=C/C)/C(=O)NC(C(=O)NCC(=O)NC(C(=O)N2)CCC(=O)N)[C@H](CC(=O)N)O)NC(=O)[C@H](NC1=O)[C@@H](C)O)O)N=CN3)C)O)OC5[C@H]([C@H]([C@@H](CO5)O)O)O

  • Graph inference:



  • Monomeric composition :
    1
    aThr
    2
    Tyr
    3
    dhAbu
    4
    bOH-Gln
    5
    Gly
    6
    Gln
    7
    His
    8
    Dab
    9
    C14:2(t4.t6)-OH(2.3)
    10
    Lyx
    11
    dhAbu
  • Graph representation: aThr,Tyr,dhAbu,bOH-Gln,Gly,Gln,His,Dab,C14:2(t4.t6)-OH(2.3),Lyx,dhAbu @7,1 @0,2,6 @1,3 @2,4 @3,5 @4,6 @7,5,1 @10,0,6 @9,10 @8 @8,7

  • Atomic structure:
    Chemical structure
  • Aciculites orientalis
  • taxid: 1562474 (view NCBI taxonomy browser)

  • Links between organisms producing the aciculitin B: Aciculites orientalis
  • Aciculitins A-C: Cytotoxic and antifungal cyclic peptides from the lithistid sponge Aciculites orientalis
    Williams DH, Faulkner DJ, Bewley CA, He H, Journal of the American Chemical Society , 1996, 118 (18), pp. 4314-4321


back Return to annotations search