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amphomycin A1437 E


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  • Norine ID: NOR00764
  • Family: friulimicin
  • Synonym(s): amphomycin A1437 E;
  • Activity: antibiotic
  • Class: lipopeptide
  • Formula: C58H91N13O20
  • Monoisotopic mass: 1289.650332417 g/mol
  • Comment: The acyl residue is essential for antibiotic activity.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2008-08-04 by Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Actinoplanes friuliensis
  • gram: positive
  • taxid: 196914 (view NCBI taxonomy browser)

  • Streptomyces canus
  • gram: positive
  • taxid: 58343 (view NCBI taxonomy browser)

  • Links between organisms producing the amphomycin A1437 E: Actinoplanes friuliensis, Streptomyces canus
  • An acyl-CoA dehydrogenase is involved in the formation of the Delta cis3 double bond in the acyl residue of the lipopeptide antibiotic friulimicin in Actinoplanes friuliensis
    Heinzelmann E, Berger S, Muller C, Hartner T, Poralla K, Wohlleben W, Schwartz D, Microbiology , 2005, Jun,151(Pt 6):1963-74.
    pubMed: 15942003
  • Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides
    Grunewald J, Marahiel MA, Microbiology and molecular biology reviews : MMBR , 2006, Mar,70(1):121-46.
    pubMed: 16524919


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