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chloropolysporin B


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  • Norine ID: NOR00932
  • DOI: 10.26097/nor00932
  • Family: chloropolysporin
  • Synonym(s): chloropolysporin B;
  • Activity: antibiotic
  • Class: glycopeptide
  • Formula: C83H89Cl3N8O34
  • Monoisotopic mass: 1846.454675166 g/mol
  • Comment: Two bonds of the central Hpg are due to oxidative ring closure.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: other
  • Number of monomers: 11
  • Smiles: CNC(c1ccc(cc1)OC2OC(C)C(O)C(O)C2(O))C(=O)NC%14C(=O)NC(c3ccc(O)c(c3)Cl)C(=O)NC6c%11cc(Oc4ccc(cc4Cl)C(OC5CC(N)C(O)C(C)O5)C8NC(=O)C(NC6(=O))c7ccc(O)c(c7)c9c(O)cc(O)cc9(C(NC8(=O))C(=O)O))c(OC%10OC(CO)C(O)C(O)C%10(O))c(c%11)Oc%12ccc(cc%12Cl)C%14(OC%13OC(CO)C(O)C(O)C%13(O))

  • Graph inference:



  • Monomeric composition :
    1
    NMe-Hpg
    2
    Cl-Tyr
    3
    D-Man
    4
    Cl-Hpg
    5
    Hpg
    6
    D-Glc
    7
    bOH-Cl-Tyr
    8
    Ria
    9
    Dhpg
    10
    Hpg
    11
    Rha
  • Graph representation: NMe-Hpg,Cl-Tyr,D-Man,Cl-Hpg,Hpg,D-Glc,bOH-Cl-Tyr,Ria,Dhpg,Hpg,Rha @1,10 @0,2,4,3 @1 @4,1 @1,3,5,6,9 @4 @4,8,9,7 @6 @9,6 @4,8,6 @0

  • Atomic structure:
    Chemical structure
  • Faenia interjecta
  • gram: positive
  • synonyms: Saccharopolyspora

  • Links between organisms producing the chloropolysporin B: Faenia interjecta
  • Chloropolysporins A, B and C, novel glycopeptide antibiotics from Faenia interjecta sp. nov. V. Comparative studies of the biological properties
    Katayama T, Takatsu T, Nakajima M, Takahashi S, Haneishi T, Magaribuchi T, The Journal of antibiotics , 1987, Jul,40(7):946-52.
    DOI: 10.7164/antibiotics.40.946
    pubMed: 3624073


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