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polymyxin M


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  • Norine ID: NOR01062
  • DOI: 10.26097/nor01062
  • Family: polymyxin
  • Synonym(s): polymyxin M;
  • Activity: antimicrobial
  • Class: lipopeptide
  • Formula: C51H97N16O14
  • Monoisotopic mass: 1157.737016892 g/mol
  • Comment: It contain 6-methyloctanoicacid
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 11
  • Smiles: CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1(=O))C(C)O)C(C)O

  • Graph inference:



  • Monomeric composition :
    1
    aC9:0
    2
    Dab
    3
    Thr
    4
    Dab
    5
    Dab
    6
    Dab
    7
    D-Leu
    8
    Thr
    9
    Dab
    10
    Dab
    11
    Thr
  • Graph representation: aC9:0,Dab,Thr,Dab,Dab,Dab,D-Leu,Thr,Dab,Dab,Thr @1 @0,2 @1,3 @2,4 @3,5,10 @4,6 @5,7 @6,8 @7,9 @8,10 @4,9

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Paenibacillus kobensis
  • gram: positive
  • synonyms: Bacillus kobensis
  • taxid: 59841 (view NCBI taxonomy browser)

  • Links between organisms producing the polymyxin M: Paenibacillus kobensis
  • Isolation, structural characterization, and properties of mattacin (polymyxin M), a cyclic peptide antibiotic produced by Paenibacillus kobensis M
    Churey JJ, Worobo RW, Martin NI, Hu H, Moake MM, Whittal R, Vederas JC, The Journal of biological chemistry , 2003, Apr 11,278(15):13124-32.
    DOI: 10.1074/jbc.M212364200
    pubMed: 12569104


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