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arylomycin A2


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  • Norine ID: NOR01115
  • DOI: 10.26097/nor01115
  • Family: arylomycin
  • Synonym(s): arylomycin A2;
  • Activity: antibiotic
  • Class: lipopeptide
  • Formula: C42H60N6O11
  • Monoisotopic mass: 824.432006792 g/mol
  • Comment: Arylomycins represent the first examples of biaryl-bridged lipopeptides.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative
    • last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 7
  • Smiles: C[C@H]1C(=O)N[C@@H](CC2=CC(=C(C=C2)O)C3=C(C=CC(=C3)[C@@H](C(=O)N1)N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](CO)N(C)C(=O)CCCCCCCCC(C)C)O)C(=O)O

  • Graph inference:



  • Monomeric composition :
    1
    iC12:0
    2
    D-NMe-Ser
    3
    D-Ala
    4
    Gly
    5
    NMe-Hpg
    6
    Ala
    7
    Tyr
  • Graph representation: iC12:0,D-NMe-Ser,D-Ala,Gly,NMe-Hpg,Ala,Tyr @1 @0,2 @1,3 @2,4 @3,5,6 @4,6 @4,5

  • Atomic structure:
    Chemical structure
  • Streptomyces sp. Tu 6075
  • gram: positive

  • Links between organisms producing the arylomycin A2: Streptomyces sp. Tu 6075
  • Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tu 6075. II. Structure elucidation
    Jung G, Holtzel A, Schmid DG, Nicholson GJ, Stevanovic S, Schimana J, Gebhardt K, Fiedler HP, The Journal of antibiotics , 2002, Jun,55(6):571-7.
    DOI: 10.7164/antibiotics.55.571
    pubMed: 12195963


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